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Tafnat 25mg Tablet is manufactured by Natco which helps to treat hepatitis c virus infection and also used in the treatment of hiv in adults.
Brand Name: Tafnat
Contents: Tenofovir Alafenamide Fumarate
Marketed By: Natco Pharma Limited
Packing: Pack of 28 tablets
Mechanism of Action
Tafnat (Tenofovir Alafenamide Fumarate(TAF)) is a Nucleotide Reverse Transcriptase Inhibitor (NRTI) and a novel ester prodrug of the antiretroviral,tenofovir. Following oral administration, TAF is converted in vivo to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analog of adenosine monophosphate. Tenofovir mimics normal DNA building blocks but is lacking a OH molecule required for phosphodiester bond linkage. By competing with regular nucleotides for incorporation into proviral DNA and prevention of the formation of phosphodiester linkage required for DNA elongation, tenofovir causes early chain termination and prevents proviral DNA transcription.
The Pharmacokinetic (PK) properties of TAF are given below. The multiple dose PK parameters of TAF and its metabolite, tenofovir.
The common side effects while you take Tafant (Tenofovir Alafenamide Fumarate) treatment
Consult with your doctor before you taking this Tafnat 25mg medicine. If you face any severe side effects such as
â€¢ Low red blood cells, weakness, rapid heart rate
â€¢ Trouble in concentrating
â€¢ weak or shallow breathing
â€¢ Slow heartbeats
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