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Availability: In stock

Special Price $ 525

BRAND : Abirapro
STRENGTH : 250mg
INGREDIENT : Anticancer-Cancer-Treatment-Glenmark-Abiraterone-Acetate-250mg-Abirapro
COUNT : 120 Tablets

Description of Abirapro

Generic: Abiraterone Brand: Abirapro 250mg Mfg: BDR pharmaceuticals Marketed by: Glenmark Abirapro Description: Abirapro is one of the antineoplastic agents that involved in the reduction of androgen production in the body. Androgens, it is a male hormone which is responsible for tumor cells formation in prostate glands

Pharmacology of Abirapro

Mechanism of action: Tablet Abirapro is an anti androgen medication, which leads to eradicate the enzyme 17α-hydroxylase C 17, 20-lyase (CYP17), it is involved in androgen synthesis. Reduce the serum testosterone level. Depletion of tumor cell occurred Pharmacokinetics: Absorption of tablet Abirapro: The median plasma concentration of tablet Abirapro takes 12 hours. Distribution of Abirapro tablets Tablet Abirapro is highly bound to the plasma protein like albumin and alpha-1 acid glycoprotein. Metabolism of Abirapro tablets The two main metabolites of Abiraterone in human plasma are Abiraterone sulphate and N-oxide Abiraterone sulphate. Excretion of Abirapro tablets The mean terminal half life of tablet Abirapro is 12 ± 5 hours. It is mainly excreted in 88% faeces and 5% in urine.

Indication of Abirapro

Abirapro tablet is used in male patient for the treatment of Metastatic castration resistant prostate cancer.

Dose & Dosage's of Abirapro

The recommended dose of the tablet Abirapro is 1000mg/day Tablet Abirapro is taken as 4 tablet as a single dose. Abirapro should be combined with prednisolone as twice daily to reduce the risk of side effects. Abirapro tablet administered with whole water, do not crush and open the capsules.

Side Effects of Abirapro

Swelling of feet, pain in legs, burning sensation while urination, hypertension, severe headache, blurred vision, pounding in neck or ear, nose bleed, anxiety, chest pain, difficulty breathing, hyperglycemia, increased thirst, urination, hunger, dry mouth, fruity odor, dry skin, weight loss, liver problems, nausea, vomiting, loss of appetite, urinary tract infection, decreased potassium levels Common side effects may include: * Vomiting * Diarrhea * Painful or difficult urination * Swelling; feeling weak * Feeling very hot * Joint pain or swelling * Bruising; or cough, * Shortening of breath

Contraindication of Abirapro

Abirapro is highly contraindicated in the conditions like; Pregnancy, breast feeding Abirapro cause hypersensitivity reaction to the patients

Drug Interaction of Abirapro

Common medication causes drug interaction with tablet Abirapro; * Fexofenadine * lcohol containing medicines like ethanol * Tadalafil * Dexamethasone

Precaution of Abirapro

Caution must be taken in patient having; Adrenal problems Heart problem Liver problems Important safety measures: Abirapro not used in patient having severe liver disease. Abirapro cause fetal death or birth defects, it should not be used by pregnant women or who may become pregnant. Nursing mother also not taking Abirapro, it is excreted in human milk which cause harm to nursing babies.

Usage & Safety profile of Abirapro Pregnancy & Lactation

Abirapro should not give to pregnancy and lactation period. Abirapro comes under pregnancy category X, so it causes fetal death.

Storage of Abirapro

Abirapro stored at below 30oC. Abirapro tablet container keep away from heat, moisture. Protect from light.