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Virso

HepatitisC-Strides-Sofosbuvir-400mg-Virso

Availability: In stock

Special Price $ 425

BRAND : Virso
STRENGTH : 400mg
INGREDIENT : HepatitisC-Strides-Sofosbuvir-400mg-Virso
COMPANY NAME : Strides
COUNT : 28 Tablets



Description of Virso

Product Specification:
Trade Name :Sovaldi
Brand Name : Virso
Composition : Sofosbuvir
Manufactured by : Strides ArcolabLtd
Dose : Sofosbuvir 400 mg
Dosage Form : Tablets
Pack of 28 tablets in a bottle
Virso is a generic version of sovaldi and manufactured by Strides Arcolab.Ltd. Virso is type of classification of antiviral medication, it contain Sofosbuvir as active ingredient. Virso is prescription depended drug should be dispensed under the advice of the consultant.

Pharmacology of Virso

Pharmacodynamic :
Mechanism of action:
Virso is a nucleotide polymerase inhibitor and includes in direct acting antiviral drug. Virso expose to have a high barrier to the development of resistance and inhibits the hep C NS5B protein. Thereby Virso prevents the enzyme RNA polymerase by the cellular worker who can performs the multiplication process, Hence Virso stops the replication of Hepatitis C virus and decrease the amount of Hep C virus in liver. Virso also acts to reduce damage in liver and improves function in liver.
Pharmacokinetic:
Absorption: Administration of Virso was absorbed with peak plasma concentration of obtained at -0.5 to 2 hr post dose and in metabolite GS-331007 peak plasma concentration obtained between 2 to 4 hrs post dose.
Effect of food: Virso and the metabolite have no affect with high fat meal. Hence virso is administrated without food is effective.
Distribution: Virso is approx 51-65% bound to human plasma proteins and GS-331007 metabolite has minimal human plasma protein binding.
Metabolism: In liver, Virso is broadly metabolized(4% and >90%) to convert into pharmacologically active nucleoside analog triphosphate GS-461203.
Elimination: Mean total recovery of the Virso dose was >92%, involves of approx 80%,14% and 2.5% eliminated in urine, feces, expired air.
Half life of Virso and GS-331007 were 0.4 and 27hrs.

Indication of Virso

Virso is used to for the treatment of severe Hepatitis C virus in the liver, Hepatitis C virus is a long lasting infection of liver, Virso is highly effective medicine for this infection. Therefore Virso will decrease the action of hepatitis C Virus in our body and recover the liver from infection caused by virus.

Dose & Dosage's of Virso

Dose recommended for Virso medication is one tablet of 400mg OD (once daily) taken orally given along with food or without . Duration of Virso for genotype 1 or 4 and 2 (CHC) is 12 weeks and Genotype 3 (CHC) is 24 weeks.

Side Effects of Virso

Virso has common and serious effects:
Nausea and vomiting
Chills and fever
Pharyngtitis
Skin in pale colour
Lumbar pain
Myalgia
Weakness
Sleeping trouble
Diarrhea

Contraindication of Virso

Virso has no specific contraindications when used alone. When Virso in combination with ribavirin or peginterferon alfa/ribavirin, or others, the contraindications also applicable to these agents are applied.

Drug Interaction of Virso

Virso is used to for the treatment of severe Hepatitis C virus in the liver, Hepatitis C virus is a long lasting infection of liver, Virso is highly effective medicine for this infection. Therefore Virso will decrease the action of hepatitis C Virus in our body and recover the liver from infection caused by virus.

Precaution of Virso

Patients undergoing treatment for Hepatitis C with Virso will require routine check up to their physician and blood check up to be followed..
Risk of birth defect or harm to unborn baby, so pregnancy time, Virso should avoided.
Allergic to Sofosbuvir alone, then inform your consultant.
Virso Co-administration with amiodarone may occur serious bradycardia.

Usage & Safety profile of Virso Pregnancy & Lactation

Virso alone assigned a pregnancy category B, In all trimester there are no adequate and well tolerated studies in pregnant women, Since animal reproduction trial has no risks and adverse effect to the fetus. But Virso combination with ribavirin, assigned a pregnancy category X leads to birth defect and death to the fetus. Avoid combination therapy during pregnancy. While breast feeding the drugs pass into breast milk is unknown, therefore its recommended that mother should not breast feed during Virso alone and combination treatment.

Storage of Virso

Virso 400 mg tablet should store below 300C (860F)
Virso Should be placed in cool and dry place
Virso should be packed in original container with sealed cap
Improper storage of Virso will affect efficacy and shelf life
Virso should not kept in the glove compartment of a car. Regimen can get too hot, cold, or wet .