Description of HepBest
Mechanism of Action Hepbest (Tenofovir Alafenamide Fumarate (TAF)) is a Nucleotide Reverse Transcriptase Inhibitor (NRTI) and a novel ester prodrug of the antiretroviral,tenofovir. TAF is converted in vivo to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analog of adenosine monophosphate. Tenofovir mimics normal DNA building blocks but is lacking OH molecule required for phosphodiester bond linkage. By competing with regular nucleotides for incorporation into proviral DNA and prevention of the formation of phosphodiester linkage required for DNA elongation, tenofovir causes early chain termination and prevents proviral DNA transcription. Drug Interactions Coadministration of Hepbest with drugs that reduce renal function or compete for active tubular secretion may increase concentrations of tenofovir and other renally eliminated drugs and this may increase the risk of adverse reactions. Indications and Usage Hepbest 25mg tablet is indicated for the treatment of chronic HBV infection in adults with compensated liver disease. Administration and Dosage The recommended dosage of HepBest 25mg tablets in for adults is once a day. Take this medicine orally once daily with food. Storage and Handling Store below 30Ã‚Â°C (86Ã‚Â°F). Keep container tightly closed Dispense only in original container Buy HepBest 25mg From Apple Pharmaceuticals Apple Pharmaceuticals offer this Hepatitis B and Anti hiv drugs Hepbest 25mg at best price in india. to buy hepbest 25mg call/whatsapp +91-9987711567.