Tafero 25mg Tablet is manufactured by Hetero which helps to treat HIV in adults and also used in the treatment of hepatitis b virus (HBV) infection.
Brand Name: Tafero
Contents: Tenofovir Alafenamide Fumarate
Marketed By: Hetero
Packing: Pack of 28 tablets
Mechanism of Action
Tenofovir Alafenamide Fumarate (TAF) 25mg tablet is a Nucleotide Reverse Transcriptase Inhibitor (NRTI) and a novel ester prodrug of the antiretroviral,tenofovir. Following oral administration, TAF is converted in vivo to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analog of adenosine monophosphate. Tenofovir mimics normal DNA building blocks but is lacking an OH molecule required for phosphodiester bond linkage. By competing with regular nucleotides for incorporation into proviral DNA and prevention of the formation of phosphodiester linkage required for DNA elongation, tenofovir causes early chain termination and prevents proviral DNA transcription.
The Pharmacokinetic (PK) properties of TAF are given below. The multiple dose PK parameters of TAF and its metabolite, tenofovir.
Consult with your doctor before you taking this Tafero 25mg medicine. If you face any severe side effects such as
Low red blood cells, weakness, rapid heart rate
Trouble in concentrating
Weak or shallow breathing
The common side effects while you take Tafero (Tenofovir Alafenamide Fumarate 25mg tablet) treatment
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